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Yale Fertility Center

The Yale Section of Reproductive Endocrinology and Infertility (Yale REI) delivers specialized gynecologic care regarding women's hormonal, menstrual and fertility issues throughout the lifespan. All problems related to abnormal puberty, irregular or absent menstruation, cystic ovaries, heavy menstrual bleeding, infertility (both male and female), fibroids, alternatives to hysterectomy and menopausal medicine are included within this discipline.

Yale REI features care starting with the maturation of young women at the time of puberty. We have a specialist in pediatric and adolescent gynecology available for consultation. Dr. Beth Rackow has a special interest in variability of progression through puberty and issues surrounding irregular or painful menstruation in adolescents.

During the mid-reproductive years, fertility often becomes a concern. There is a rising incidence of infertility in our country today. Yale REI provides comprehensive infertility services. All members of the section are involved in treatment of infertility resulting from tubal blockage, anovulation, endometriosis, uterine disease, and male infertility. We offer diagnosis of the etiology of infertility as well as comprehensive treatment programs. These treatments include ovulation induction, intrauterine insemination, in vitro fertilization, intracytoplasmic sperm injection (ICSI), and sperm retrieval.

In addition, our IVF laboratory offers the newest advances in embryo diagnosis and selection. A team of experts offer embryo biopsy with preimplantation genetic diagnosis done on the premises for rapid turnaround and accurate results. We offer diagnosis of genetic disorders, as well as chromosomal abnormalities. New innovative techniques for selection of the optimal embryo are being developed at Yale REI. We also offer embryo cryopreservation for preserving embryos for use in future cycles. Dr. Denny Sakkas is a world-renowned embryologist who directs our IVF Laboratory team. Other members of the team include Drs. Dagan Wells and Maria Lalioti. They, along with other staff, provide the most state-of-the-art and comprehensive laboratory for IVF found anywhere.

In addition to taking care of immediate fertility needs, we also offer oocyte cryopreservation. While still experimental, the technique is being pioneered at Yale with our collaborators. Dr. Pasquale Patrizio offers ovarian and oocyte cryopreservation to preserve fertility for those undergoing chemotherapy, radiation therapy, or who may be contemplating deferring childbearing for many reasons.

Finally, as the natural supply of eggs is exhausted at the end of the reproductive age range, we offer a state-of-the-art oocyte donation program. Directed by Dr. Emre Seli, our Donor Egg Program boasts one of the highest success rates in the country. We have an outstanding pool of oocyte donors to assure a continuous supply of high quality eggs.

Other common reproductive tract complaints that occur during a woman's reproductive life include endometriosis, polycystic ovarian syndrome, and irregular and abnormal uterine bleeding. Yale is one of three designated specialized centers for endometriosis research. Dr. Hugh Taylor is Chief of Yale REI and an expert in advanced treatment of endometriosis. In addition to comprehensive surgical therapy, we also offer some of the latest advances in hormonal treatment. There has been rapid progress in these areas and many new products have become available for use in endometriosis therapy over the last few years. We continue to offer state-of-the-art treatment and are participating in the development of several new agents for the treatment of endometriosis.

Uterine fibroids and abnormal bleeding continue to be a major women's health problem. Approximately 600,000 hysterectomies are performed in the United States each year, many of them as treatment for abnormal bleeding. But often the abnormal bleeding can be treated without the need for a hysterectomy. We offer advanced medical treatment for abnormal uterine bleeding that may avoid surgical procedures. We also offer advanced hysteroscopic surgery and endometrial cryoablation as minimally invasive alternatives to hysterectomy.

Finally, polycystic ovary syndrome is a disorder characterized not only by abnormal cysts on the ovaries and irregular menstrual cycles, but also by is frequently associated with diabetes and changes in insulin and sugar levels. While traditional treatment has often consisted of birth control pills, we offer total treatment of this condition, including all of the associated metabolic abnormalities. We also offer customized regimens of agents like Metformin (glucophage) that will improve the response to insulin and often ameliorate this condition. We offer comprehensive specialized care for this condition that goes beyond simply eliminating the menstrual irregularities. We also participate in several national trials examining new means of treating polycystic ovarian syndrome.

Finally, the end of the reproductive life span is marked by transitioning into menopause. Treatment of menopausal symptoms has been a difficult and controversial topic. Yale REI participates in the KEEPS Trial that is investigating the effects of timing of intervention with hormone therapy. We have also participated in multiple other research studies of the menopausal transition period. We offer comprehensive counseling of the benefits and risks of hormone therapy.

Yale REI is leading the way in reproductive endocrinology and infertility. We offer the most advanced care available anywhere. Yale REI is also conducting some of the state-of-the-art research that is advancing the field. We are pleased to offer the most advanced care available anywhere, delivered by a compassionate team of caring internationally recognized experts.

Contacting Us

To make an appointment or for more information about our full range of fertility services, call us at (203) 785-4708 or toll free at 1-877-Yale-IVF. You may also visit our comprehensive and user-friendly website that contains information about us, our programs and services, and directions to Yale Fertility Center.
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